@article{
	11589_1343,
	author = { Boccaccio A  and  Martino F  and  Pappalettere C },
	title = {A Novel Moiré-based Optical Scanning Head for High Precision Contouring},
	year = {9999},
	journal = {INTERNATIONAL JOURNAL OF ADVANCED MANUFACTURING TECHNOLOGY}
}
@article{
	11589_61745,
	author = { Boccaccio  Antonio  and  Uva  Antonio Emmanuele  and  Fiorentino  Michele  and  Mori  Giorgio  and  Monno  Giuseppe },
	title = {Geometry Design Optimization of Functionally Graded Scaffolds for Bone Tissue Engineering: A Mechanobiological Approach},
	year = {2016},
	journal = {PLOS ONE},
	volume = {11},
	abstract = {Functionally Graded Scaffolds (FGSs) are porous biomaterials where porosity changes in space with a specific gradient. In spite of their wide use in bone tissue engineering, possible models that relate the scaffold gradient to the mechanical and biological requirements for the regeneration of the bony tissue are currently missing. In this study we attempt to bridge the gap by developing a mechanobiology-based optimization algorithm aimed to determine the optimal graded porosity distribution in FGSs. The algorithm combines the parametric finite element model of a FGS, a computational mechano-regulation model and a numerical optimization routine. For assigned boundary and loading conditions, the algorithm builds iteratively different scaffold geometry configurations with different porosity distributions until the best microstructure geometry is reached, i.e. the geometry that allows the amount of bone formation to be maximized. We tested different porosity distribution laws, loading conditions and scaffold Young's modulus values. For each combination of these variables, the explicit equation of the porosity distribution law-i.e the law that describes the pore dimensions in function of the spatial coordinates-was determined that allows the highest amounts of bone to be generated. The results show that the loading conditions affect significantly the optimal porosity distribution. For a pure compression loading, it was found that the pore dimensions are almost constant throughout the entire scaffold and using a FGS allows the formation of amounts of bone slightly larger than those obtainable with a homogeneous porosity scaffold. For a pure shear loading, instead, FGSs allow to significantly increase the bone formation compared to a homogeneous porosity scaffolds. Although experimental data is still necessary to properly relate the mechanical/biological environment to the scaffold microstructure, this model represents an important step towards optimizing geometry of functionally graded scaffolds based on mechanobiological criteria.},
	doi = {10.1371/journal.pone.0146935},	
}
@conference{
	11589_18453,
	author = { Sciammarella CA  and  Lamberti L  and  Boccaccio A },
	title = {Determination of cardiac wall deformations from MRI images},
	year = {2016},
	publisher = {Springer},
	address = {New York},
	volume = {6},
	booktitle = {Mechanics of Biological Systems and Materials - Proceedings of the 2015 SEM Annual Conference on Experimental and Applied Mechanics},
	abstract = {Three-dimensional deformation analysis of human organs is very important from both diagnostic and therapeutic point of view. For example, comparing the deformation field in healthy and pathologic cardiac walls in the systolic phase allows to gather early and accurate information on the onset of heart diseases. MRI tagging is utilized in medicine to visualize with a great deal of detail the structure and morphology of tissues. The tagging process introduces a volumetric system of planes of reference similar to the process of introducing a grating in the 3-D moiré method in transparent media. The paper will analyze the kinematics of 3-D deformation fields and the fundamental concepts involved in 3-D deformation analysis within the restrictions imposed by the MRI method thus providing solutions for the inherent shortcomings encountered in the MRI tagging technique.},
	doi = {10.1007/978-3-319-21455-9_8},	
	pages = {69--83}
}
@conference{
	11589_18456,
	author = { Boccaccio A  and  Lamberti L  and  Papi M  and  De Spirito M  and  Pappalettere C },
	title = {A deeper look into immature porcine zona pellucida visco-hyperelasticity},
	year = {2016},
	publisher = {Springer},
	address = {New York},
	volume = {6},
	booktitle = {Mechanics of Biological Systems and Materials. Volume 6. Proceedings of the 2015 SEM Annual Conference on Experimental and Applied Mechanics},
	abstract = {The usual assumption made in mechanical characterization of soft biotissues with Atomic Force Microscopy (AFM) is that the specimen behaves as a purely elastic material. However, there is a limit indentation rate below which viscous effects can be neglected. A parametric study including about 200 FEM analyses shows that in the case of immature porcine zona pellucida (ZP) samples viscous effects become more significant for sharp tips. A linear relationship between the limit indentation rate and the geometry of the AFM probe is derived for the porcine ZP samples analyzed in this study},
	doi = {10.1007/978-3-319-21455-9_9},	
	pages = {85--89}
}
@article{
	11589_60468,
	author = { Boccaccio A  and  Uva AE  and  Fiorentino M  and  Lamberti L  and  Monno G },
	title = {A mechanobiology-based algorithm to optimize the microstructure geometry of bone tissue scaffolds},
	year = {2016},
	journal = {INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES},
	volume = {12},
	abstract = {Complexity of scaffold geometries and biological mechanisms involved in the bone generation process make the design of scaffolds a quite challenging task. The most common approaches utilized in bone tissue engineering require costly protocols and time-consuming experiments. In this study we present an algorithm that, combining parametric finite element models of scaffolds with numerical optimization methods and a computational mechano-regulation model, is able to predict the optimal scaffold microstructure. The scaffold geometrical parameters are perturbed until the best geometry that allows the largest amounts of bone to be generated, is reached. We study the effects of the following factors: (1) the shape of the pores; (2) their spatial distribution; (3) the number of pores per unit area. The optimal dimensions of the pores have been determined for different values of scaffold Young’s modulus and compression loading acting on the scaffold upper surface. Pores with rectangular section were predicted to lead to the formation of larger amounts of bone compared to square section pores; similarly, elliptic pores were predicted to allow the generation of greater amounts of bone compared to circular pores. The number of pores per unit area appears to have rather negligible effects on the bone regeneration process. Finally, the algorithm predicts that for increasing loads, increasing values of the scaffold Young’s modulus are preferable. The results shown in the article represent a proof-of-principle demonstration of the possibility to optimize the scaffold microstructure geometry based on mechanobiological criteria},
	doi = {10.7150/ijbs.13158},	
	pages = {1--17}
}
@article{
	11589_1279,
	author = { Boccaccio A  and  Lamberti L  and  Papi M  and  De Spirito M  and  Pappalettere C },
	title = {Effect of AFM probe geometry on visco-hyperelastic characterization of soft materials},
	year = {2015},
	journal = {NANOTECHNOLOGY},
	volume = {26},
	abstract = {Atomic force microscopy (AFM) nanoindentation is very suited for nano- and microscale mechanical characterization of soft materials. Although the structural response of polymeric networks that form soft matter depends on viscous effects caused by the relative slippage of polymeric chains, the usual assumption made in the AFM-based characterization is that the specimen behaves as a purely elastic material and viscous forces are negligible. However, for each geometric configuration of the AFM tip, there will be a limit indentation rate above which viscous effects must be taken into account to correctly determine mechanical properties. A parametric finite element study conducted on 12 geometric configurations of a blunt cone AFM tip (overall, the study included about 200 finite element analyses) allowed us to determine the limit indentation rate for each configuration. The selected tip dimensions cover commercially available products and account for changes in tip geometry caused by serial measurements. Nanoindentation rates cover typical experimental conditions set in AFM bio-measurements on soft matter. Viscous effects appear to be more significant in the case of sharper tips. This implies that, if quantitative data on sample viscosity are not available, using a rounded indenter and carrying out experiments below the limit indentation rate will allow errors in the determination of mechanical properties to be minimized.},
	doi = {10.1088/0957-4484/26/32/325701},	
}
@article{
	11589_61746,
	author = { Pettini  Francesco  and  Corsalini  Massimo  and  Savino  Maria Grazia  and  Stefanachi  Gianluca  and  Di Venere  Daniela  and  Pappalettere  Carmine  and  Monno  Giuseppe  and  Boccaccio  Antonio },
	title = {Roughness analysis on composite materials (Microfilled, nanofilled and silorane) after different finishing and polishing procedures},
	year = {2015},
	journal = {THE OPEN DENTISTRY JOURNAL},
	volume = {9},
	abstract = {The finishing and polishing of composite materials affect the restoration lifespan. The market shows a variety of finishing and polishing procedures and the choice among them is conditioned by different factors such as the resulting surface roughness. In the present study, 156 samples were realized with three composite materials, -microfilled, nanofilled and silorane-, and treated with different finishing and polishing procedures. Profilometric analyses were carried out on the samples' surface, the measured roughness values were submitted to statistical analysis. A complete factorial plan was drawn up and two-way analysis of variance (ANOVA) was carried out to investigate whether the following factors affect the values of roughness: (i) material; (ii) polishing/finishing procedure. Tukey post-hoc test was also conducted to evaluate any statistically significant differences between the material/procedure combinations. The results show that the tested materials do not affect the resulting surface quality but roughness values depend on the finishing/polishing procedure adopted. The procedures that involve: (a) the finishing with medium Sof-Lex discs and (b) the finishing with two tungsten carbide multi-blade milling cutters Q series and UF series are those that allow the lowest values of roughness to be obtained.},
	keywords = {Composite; Finishing; Polishing; Profilometer; Surface roughness; Dentistry (all)},
	url = {http://www.benthamscience.com/open/todentj/index.htm},
	doi = {10.2174/1874210601509010357},	
	pages = {357--367}
}
@conference{
	11589_16538,
	author = { Boccaccio A  and  Brunelli R  and  Lamberti L  and  Papi M  and  Parasassi T  and  De Spirito M  and  Pappalettere C },
	title = {A preliminary investigation on the mechanical behavior of umbilical cord with moiré techniques},
	year = {2015},
	publisher = {Springer},
	address = {NEW YORK},
	volume = {3},
	booktitle = {Proceedings of the 2014 SEM Annual Conference on Experimental and Applied Mechanics, Greenville (USA), June 2014. Volume 3: Advancement of Optical Methods in Experimental Mechanics},
	abstract = {The umbilical cord is a peculiar and complex structure, about 50–60 cm in length and 1–2 cm in diameter, that is essentially composed of three vessels, i.e. the umbilical vein and two umbilical arteries, arranged in coils around the vein surrounded by a great amount of support tissue, the Wharton’s Jelly (WJ) that binds and encases the umbilical vessels. WJ is a mucoid connective tissue (5 % cells, 95 % extracellular matrix) described as a three-dimensional spongy network of interlacing collagen fibers and small woven bundles of glycoprotein microfibrils with an interdispersed soluble phase composed by hydrophylic hyaluronans and proteoglycans. WJ grants the protection of the umbilical vessels against compressive forces due to fetal movements and uterine contractions and is very important to guarantee venous and arterial umbilical blood flows. WJ response to mechanical loading is not well understood; another unsolved problem concerns WJ putative contribution to store and release the energy of the cardiac cycle, therefore in maintaining the anterograde flow in the cord arteries. This article presents a preliminary study on the mechanical behavior of umbilical cord. For that purpose, an optical set up based on intrinsic moire´ will be developed. Slices cut in the transverse directions of the cord will be submitted to equibiaxial tests and specimen deformations will be monitored in real time with moire´ by printing a grating on the cord slice. In this way, it will be possible to gather information on the mechanical anisotropy of the cord},
	doi = {10.1007/978-3-319-06986-9_5},	
	pages = {47--52}
}
@conference{
	11589_16549,
	author = { Boccaccio A  and  Lamberti L  and  Papi M  and  Douet C  and  Goudet G  and  De Spirito M  and  Pappalettere C },
	title = {Study on the visco-hyperelastic behavior of the zona pellucida},
	year = {2015},
	publisher = {Springer},
	address = {NEW YORK},
	volume = {3},
	booktitle = {Proceedings of the 2014 SEM Annual Conference on Experimental and Applied Mechanics, Greenville (USA), June 2014. Volume 3: Advancement of Optical Methods in Experimental Mechanics},
	abstract = {The zona pellucida (ZP) is a specialized extracellular matrix surrounding the developing oocyte. This thick matrix consists of different types of glycoprotein, which have different roles in fertilization. Nowadays several techniques are developed and refined to establish the ZP mechanical response. The assumption at the basis of these methods is that the ZP behaves like an elastic body, dissipative forces are neglected, and thus the Young modulus value remains unaffected by probe dynamics. On the contrary dissipative force are strongly regulated by the slippage of ZP chains past one another whereas the absolute reaction force value is mainly due to the architecture of the ZP structure (number of cross-links and distances between knots). Elastic deflection is then due to the ability of each chain to stretch, whereas viscous flow is caused by the sliding of the molecules over one another. Therefore viscous reaction forces generated by the ZP have to be considered one of the main player in regulating the sperm transit but their peculiar behavior along the ZP structure is still poorly understood. In this context, for the first time, we developed and verified a visco-hyperelastic model able to reproduce the ZP reaction force stressed at different probe rate},
	doi = {10.1007/978-3-319-06986-9_6},	
	pages = {53--62}
}
@conference{
	11589_16548,
	author = { Sciammarella CA  and  Lamberti L  and  Boccaccio A },
	title = {Data processing techniques to analyze large 3-D deformations of cardiac cycles.},
	year = {2015},
	publisher = {Springer},
	address = {NEW YORK},
	volume = {3},
	booktitle = {Proceedings of the 2014 SEM Annual Conference on Experimental and Applied Mechanics, Greenville (USA), June 2014. Volume 3. Advancement of Optical Methods in Experimental Mechanics},
	abstract = {Quantification of 3-D deformations of human organs plays an important role in the understanding phenomena that have an impact in medical diagnosis and treatment of diseases. One important example is the mechanics of heart functions. Comparing normal deformation patterns of the cardiac cycle in healthy and diseased individuals can be a diagnostic tool that provides early and accurate indications of the onset of heart diseases. The tagging technique is an experimental mechanics method that makes it possible to utilize the extensive literature existing on the analysis of deformations utilizing the digital moire´ method for accurate and fast quantification of the heart 3-D kinematics. MRI tagging is an imaging technique used in medicine to visualize the structures of tissues of the human body in detail. MRI uses of the phenomenon of nuclear magnetic resonance to image tissues by exciting the nuclei of atoms in the tissue. Because of the different chemical composition of the tissues it can provide details that cannot be visible with CT Scans. By modulating magnetization it is possible to inscribe lattice-patterns in the tissue volume. These lattices are fixed to the under laying tissues for periods of time long enough to follow a cardiac cycle. The objective of this paper is to outline image processing techniques that can be utilized to decode the displacements and strains taking into consideration that one is dealing with large 3-D deformations that form a time sequence of images. These techniques are based on fundamental principles that have been developed in the field of digital moire´},
	doi = {10.1007/978-3-319-06986-9_7},	
	pages = {63--87}
}
@conference{
	11589_20380,
	author = { Sciammarella CA  and  Lamberti L  and  Sciammarella FM  and  Boccaccio A },
	title = {The kinematics and dynamics of 3-D displacement fields. In: Proceedings of the 2013 SEM Annual Conference on Experimental and Applied Mechanics, Lombard (USA), June 2013},
	year = {2014},
	publisher = {Springer},
	address = {NEW YORK},
	booktitle = {Advancement of Optical Methods in Experimental Mechanics (H. Jin, C.A. Sciammarella, S. Yoshida, and L. Lamberti, Eds.), Volume 3, Chapter 7},
	pages = {43--67}
}
@article{
	11589_1302,
	author = { Corsalini M  and  Di Venere D  and  Pettini F  and  Stefanachi G  and  Catapano S  and  Boccaccio A  and  Lamberti L  and  Pappalettere C  and  Carossa S },
	title = {A comparison of shear bond strength of ceramic and resin denture teeth on different acrylic resin bases},
	year = {2014},
	journal = {THE OPEN DENTISTRY JOURNAL},
	volume = {8},
	abstract = {The purpose of this study is to compare the shear bond strength of different resin bases and artificial teeth made of ceramic or acrylic resin materials and whether tooth-base interface may be treated with aluminium oxide sandblasting.
Experimental measurements were carried on 80 specimens consisting of a cylinder of acrylic resin into which a single tooth is inserted. An ad hoc metallic frame was realized to measure the shear bond strength at the tooth-base interface. A complete factorial plan was designed and a three-way ANalysis Of VAriance (ANOVA) was carried out to investigate if shear bond strength is affected by the following factors: (i) tooth material (ceramic or resin); (ii) base material (self-curing or thermal-curing resin); (iii) presence or absence of aluminium oxide sandblasting treatment at the tooth-base interface.
Tukey post hoc test was also conducted to evaluate any statistically significant difference between shear strength values measured for the differently prepared samples.
It was found from ANOVA that the above mentioned factors all affect shear strength. Furthermore, post hoc analysis indicated that there are statistically significant differences (p-value=0.000) between measured shear strength values for: (i) teeth made of ceramic material vs. teeth made of acrylic resin material; (ii) bases made of self-curing resin vs. thermalcuring resin; (iii) specimens treated with aluminium oxide sandblasting vs. untreated specimens. Shear strength values measured for acrylic resin teeth were on average 70% higher than those measured for ceramic teeth. The shear bond strength was maximized by preparing samples with thermal-curing resin bases and resin teeth submitted to aluminium oxide
sandblasting.},
	keywords = {Acrylic Resin Teeth; Ceramic Teeth; Resin Bases; Sandblasting; Shear Bond Strength},
	pages = {241--250}
}
@conference{
	11589_23353,
	author = { Pappalettere C  and  De Palma P  and  Pascazio G  and  De Tullio M  and  Camporeale S  and  Dambrosio L  and  Fortunato B  and  Torresi M  and  Fornarelli F  and  Carbone G  and  Afferrante L  and  Bottiglione F  and  Mantriota G  and  Foglia MM  and  Demelio G  and  Ciavarella M  and  Lamberti L  and  Boccaccio A  and  Ludovico AD  and  Csmpanelli SL  and  De Filippis LAC  and  Tricarico L  and  Palumbo G  and  Sorgente D  and  Scintilla LD  and  Galantucci LM  and  Percoco G  and  Lavecchia F  and  Casavola C  and  Naso N  and  Lino P  and  Maione G  and  Stasi S  and  Turchiano B  and  Cupertino F },
	title = {Advanced technologies for reduction of polluting emissions, fuel consumption and
operating costs of Heavy Duty engines, INNOVHEAD},
	year = {2014},
	volume = {Track A},
	booktitle = {Atti del "1st WORKSHOP on the State of the art and Challenges Of Research Efforts @ POLIBA"}
}
@inbook{
	11589_61774,
	author = { Boccaccio  A  and  Messina  A  and  Pappalettere  C  and  Scaraggi  M },
	title = {Finite element modelling of bone tissue scaffolds},
	year = {2014},
	publisher = {Elsevier Inc.},
	booktitle = {Computational Modelling of Biomechanics and Biotribology in the Musculoskeletal System: Biomaterials and Tissues},
	keywords = {Bone tissue engineering; Finite element modelling; Mechanobiology; Percolation analysis; Scaffold; Engineering (all); Materials Science (all)},
	url = {http://www.sciencedirect.com/science/book/9780857096616},
	doi = {10.1533/9780857096739.4.485},	
	pages = {485--511}
}
@article{
	11589_1558,
	author = { Boccaccio A  and  Lamberti L  and  Papi M  and  De Spirito M  and  Douet C  and  Goudet G  and  Pappalettere C },
	title = {A hybrid characterization framework to determine the visco-hyperelastic properties of a porcine zona pellucida},
	year = {2014},
	journal = {INTERFACE FOCUS},
	volume = {4},
	abstract = {The zona pellucida (ZP) is a specialized extracellular matrix surrounding the developing oocyte. This thick matrix consists of various types of glycoprotein that play different roles in the fertilization process. Nowadays, several techniques are available for assessing ZP’s mechanical response. The basic assumption behind these methods is that the ZP behaves like an elastic body: hence, dissipative forces are neglected and Young’s modulus remains unaffected by probe dynamics. However, dissipative forces are strongly regulated by the slippage of ZP chains past one another while reaction forces related to elastic deformations (driven by the ability of each chain to stretch) depend on the ZP  tructure (i.e. number of cross-links and distances between knots). Although viscous reaction forces generated by the ZP are one of the main factors regulating sperm transit, their peculiar behaviour along the ZP structure remains poorly understood and rarely investigated. In order to overcome this limitation, a novel visco-hyperelastic model describing the porcine ZP reaction forces generated by  anoindentations at different probe rates is developed and verified in this study. Visco-hyperelastic parameters of porcine ZP membranes are determined by means of a hybrid characterization framework combining atomic force microscopy nanoindentation measurements, nonlinear finite-element analysis and nonlinear optimization. Remarkably, it is possible to separate the contributions of hyperelastic and viscous terms to ZP mechanical response and evaluate the error made in the determination of ZP mechanical properties if viscous effects were not considered.},
	keywords = {Porcine zona pellucida; visco-hyperelasticity; atomic force microscopy; Prony series; finite-element analysis; nonlinear optimization},
	doi = {10.1098/rsfs.2013.0066},	
}
@article{
	11589_51887,
	author = { Boccaccio A  and  Casavola C  and  Lamberti L  and  Pappalettere C },
	title = {Structural response of polyethylene foam-based sandwich panels subject to edgewise compression},
	year = {2013},
	journal = {MATERIALS},
	pages = {4545--4564}
}
@inbook{
	11589_52442,
	author = { BOCCACCIO A  and  C  CASAVOLA  and  D  FRUNZIO  and  L  LAMBERTI  and  C  PAPPALETTERE },
	title = {Analysis of the mechanical behaviour of foam-based sandwich panels under edgewise compression},
	year = {2013},
	booktitle = {Procedings 12° Youth Symposium on Experimental Solid Mechanics (YSESM 2013)}
}
@conference{
	11589_52620,
	author = { Boccaccio A  and  Lamberti L  and  Papi M  and  De Spirito M  and  Maiorana A  and  Palmieri V  and  Pappalettere C },
	title = {Effetti dello stress residuo sulla caratterizzazione meccanica di membrane cellulari con Microscopia a Forza Atomica},
	year = {2013},
	booktitle = {Proceedings 42° Convegno Nazionale AIAS (Associazione Italiana di Analisi delle Sollecitazioni)}
}
@article{
	11589_52169,
	author = { C  A  SCIAMMARELLA  and  BOCCACCIO A  and  L  LAMBERTI  and  C  PAPPALETTERE  and  A  RIZZO  and  D  VALERINI },
	title = {Measurements of deflection and residual stress in thin films utilizing coherent light projection/reflection moiré interferometry},
	year = {2013},
	journal = {EXPERIMENTAL MECHANICS},
	pages = {977--987}
}
@conference{
	11589_52614,
	author = { Boccaccio A  and  Casavola C  and  Lamberti L  and  Pappalettere C },
	title = {Mechanical behavior of polyethylene foam sandwich panels under compression loading},
	year = {2013},
	booktitle = {Proceeding of IRF 2013 – 4th International Conference on INTEGRITY, RELIABILITY AND FAILURE, Funchal (Portugal), June 2013}
}